update agents md
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@@ -10,6 +10,9 @@ The main teaching example is an ICU septic shock study:
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- Teach by showing small code chunks that the user can type in manually.
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- Teach by showing small code chunks that the user can type in manually.
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- Explain each meaningful line of code before moving on.
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- Explain each meaningful line of code before moving on.
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- Add generous learner-focused comments, especially around R functions, function arguments, return values, and unfamiliar package functions.
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- Include many small examples and REPL-style checkpoints with code, expected output, and interpretation.
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- Keep report-style Quarto notebooks focused on rendered tables and interpretation unless the user asks for REPL-style checkpoints there.
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- Teach the base R mechanics when a concept is new, then prefer readable tidyverse-style code for routine analysis.
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- Teach the base R mechanics when a concept is new, then prefer readable tidyverse-style code for routine analysis.
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- Make the smallest correct change when editing project files.
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- Make the smallest correct change when editing project files.
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- Keep scripts and notebooks numbered so the learning sequence is obvious.
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- Keep scripts and notebooks numbered so the learning sequence is obvious.
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@@ -21,8 +24,11 @@ The main teaching example is an ICU septic shock study:
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- Use the native pipe `|>`, not `%>%`
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- Use the native pipe `|>`, not `%>%`
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- snake_case for all names
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- snake_case for all names
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- Prefer explicit, teaching-oriented comments over terse production-style code while this remains a learning project.
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- For reusable functions, include comments describing purpose, arguments, return value, and at least one example call.
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- Prefer `vapply` over `sapply`; explicit return types
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- Prefer `vapply` over `sapply`; explicit return types
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- Use `cli::cli_*` for messages, not `message()`/`cat()`
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- Use `cli::cli_*` for messages, not `message()`/`cat()`
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- Prefer cleaner imports with grouped startup message suppression, for example `suppressPackageStartupMessages({ library(readr); library(dplyr) })`.
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- Prefer `dplyr` verbs for data manipulation when external dependencies are allowed.
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- Prefer `dplyr` verbs for data manipulation when external dependencies are allowed.
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- Prefer `skimr` for quick data summaries.
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- Prefer `skimr` for quick data summaries.
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- Prefer `gt` and `gtsummary` for clear analytic tables in notebooks and reports.
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- Prefer `gt` and `gtsummary` for clear analytic tables in notebooks and reports.
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@@ -40,6 +46,7 @@ The main teaching example is an ICU septic shock study:
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- renv for dependency management; lockfile is source of truth
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- renv for dependency management; lockfile is source of truth
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- targets for pipeline orchestration
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- targets for pipeline orchestration
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- tidyverse, especially `dplyr`, for routine data manipulation
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- tidyverse, especially `dplyr`, for routine data manipulation
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- ggplot2 for exploratory plots and visual diagnostics
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- data.table for performance-oriented data manipulation when needed
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- data.table for performance-oriented data manipulation when needed
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- skimr for quick data summaries
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- skimr for quick data summaries
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- gt for presentation tables
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- gt for presentation tables
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@@ -53,6 +60,15 @@ The main teaching example is an ICU septic shock study:
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- Keep base R explanations available when they help the user understand what the package code is doing.
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- Keep base R explanations available when they help the user understand what the package code is doing.
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- Do not add packages outside the approved stack without asking first.
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- Do not add packages outside the approved stack without asking first.
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## Workflow Roles
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- Put reusable logic in `R/` functions.
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- Put reusable smoke checks or command-line workflows in `scripts/`.
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- Put polished displays, interpretation, exploratory visualization, and rendered result tables in Quarto notebooks.
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- Avoid CSV intermediates when functions can be called directly and reproducibly.
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- Use `run_all.sh` as the lightweight end-to-end runner until the project is ready for `targets`.
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- Keep rendered notebook reports in `outputs/reports/`.
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## Learning Roadmap
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## Learning Roadmap
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- [x] Choose ICU teaching scenario: early vasopressor strategy in septic shock.
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- [x] Choose ICU teaching scenario: early vasopressor strategy in septic shock.
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@@ -104,14 +120,16 @@ Baseline confounders in the first simulated dataset:
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- Lactate.
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- Lactate.
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- Mean arterial pressure.
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- Mean arterial pressure.
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Initial causal contrast:
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Initial estimand:
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- Risk difference in 28-day mortality.
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- Risk difference in 28-day mortality.
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- Risk ratio for 28-day mortality.
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- Risk ratio for 28-day mortality.
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## File Sequence
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## File Sequence
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- `scripts/01_simulate_icu_data_base_r.R`: generate synthetic ICU cohort data from the reusable simulation primitive.
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- `run_all.sh`: run the key scripts and render all current notebooks.
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- `scripts/02_naive_analysis_base_r.R`: compute an initial naive comparison with readable tidyverse-style code.
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- `scripts/01_simulate_icu_data.R`: simulate an ICU cohort in memory and print a quick `skimr` summary.
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- `R/simulate_icu_cohort.R`: first reusable simulation primitive.
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- `R/simulate_icu_cohort.R`: first reusable simulation primitive.
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- `notebooks/01_target_trial_basics.qmd`: conceptual walkthrough of the target trial protocol with `skimr`, `gt`, and `gtsummary` examples.
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- `R/estimate_naive_vasopressor_mortality_effect.R`: shared naive mortality-effect primitive used by notebook workflows.
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- `notebooks/01_target_trial_basics.qmd`: report-style walkthrough of the target trial protocol and initial results.
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- `notebooks/02_explore_simulated_data.qmd`: exploratory visual diagnostics for the simulated cohort.
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