17 lines
1.2 KiB
YAML
17 lines
1.2 KiB
YAML
# Experiment grids (plan sections 5.2, 7, 9). Run with simulations/run_experiment.R <grid> [--scale draft|final]
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main:
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worlds: [W0, W1, W1_rho0, W2, W3, W4, W5, WE, WR] # WE: EHR/registry-like measurement (D55)
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scenarios: ["null", harm, benefit_harm]
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designs: [naive, landmark, landmark_m5, ccw, seq] # landmark_m5: also adjusts for month-5 severity (supplement, D53)
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variants: [V1_ignore, V3_random, V4_within] # V1 also yields V2 (cluster-robust SE)
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nce: true # negative-control exposure (landmark, CCW), D32/D36
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# trims (D57): supplement-only or uninformative cells are skipped to save time
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v1_only_designs: [landmark_m5] # month-5 landmark (supplement) only without physician terms
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nce_variants: [V1_ignore, V4_within] # NCE without the random intercept
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skip_variant: {V3_random: [W0, W4]} # worlds where the physician plays no role by design
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rct: [realistic, ideal]
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scales:
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smoke: {n_patients: 20000, reps: 1}
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draft: {n_patients: 50000, reps: 100, dir: n50k_v2} # v2: D53 (landmark baseline covariates, NCO-1 severity)
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final: {n_patients: 50000, reps: 200, dir: n50k_v2} # extends the draft's replicates 1-100 to 200 (D51)
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