D53: landmark on baseline covariates (month-5 version as landmark_m5), NCO-1 depends on PVI-free severity, physician-cluster bootstrap script

Co-Authored-By: Claude Opus 5.5 <[email protected]>
2026-10-28 07:20:32 -04:00
parent fbc417662c
commit 5304c89316
10 changed files with 86 additions and 18 deletions
@@ -78,7 +78,7 @@ outcomes:
  clti_revasc: {intercept: -4.5}                      # PVI after CLTI (not elective); most CLTI patients get bypass, tibial work, amputation or nothing

 negative_controls:           # never depend on PVI
-  nco1: {intercept: -6.4, frailty: 0.5, smoking: 0.4, age10: 0.3}   # hip fracture / pneumonia
+  nco1: {intercept: -6.75, frailty: 0.5, smoking: 0.4, age10: 0.3, z: 0.3}   # hip fracture / pneumonia; z = PVI-free severity (D53)
  nco2: {intercept: -7.1, style: 0.8, venous: 0.5}                  # varicose-vein ablation
  nce:  {intercept: -5.7, style: 0.8, frailty: -0.2}                # low-value procedure, months 0-5